Onal Lab

We study genetic and epigenetic mechanisms of gene regulation during Drosophila embryo development.

  1. Bishop, T. R.*, Onal, P.*, Xu, Z.*, Zheng, M., Gunasinghe, H., Nien, C.-Y., Small, S., & Datta, R. R. (2023). Multi-level regulation of even-skipped stripes by the ubiquitous factor Zelda. Development, 150(23). https://doi.org/10.1242/DEV.201860 * Equal contribution
  2. Datta, R. R.*, & Onal, P.* (2023). In Situ Hybridization as a Method to Examine Gene Regulatory Activity In Vivo. Methods in Molecular Biology (Clifton, N.J.), 2599, 241–254. https://doi.org/10.1007/978-1-0716-2847-8_17 *Corresponding author
  3. Onal P*, Imaya Gunasinghe H, Yui Umezawa K, Zheng M, Ling J, Azeez L, Dalmeus A, Tazin T, Small S (2021) Suboptimal Intermediates Underlie Evolution of the Bicoid Homeodomain. Mol Biol Evol. https://doi.org/10.1093/molbev/msab051 *Corresponding author
  4. Liu, Q.*, Önal, P.*, Datta, R. R.*, Rogers, J. M., Schmidt-Ott, U., Bulyk, M. L., Small S., Thornton, J. W. (2018). Ancient mechanisms for the evolution of the bicoid homeodomain’s function in fly development. eLife, 7. http://doi.org/10.7554/eLife.34594 *Equal contribution
  5. Önal, P., Grün, D., Adamidi, C., Rybak, A., Solana, J., Mastrobuoni, G., Wang, Y., Rahn, H. P., Chen, W., Kempa, S., Ziebold, U. and Rajewsky, N. (2012) Gene expression of pluripotency determinants is conserved between mammalian and planarian stem cells, The EMBO Journal, 2012. https://doi.org/10.1038/emboj.2012.110.
  6. Adamidi, C., Wang, Y., Gruen, D., Mastrobuoni, G., You, X., Tolle, D., Dodt, M., Mackowiak, S. D., Gogol-Doering, A., Oenal, P., Rybak, A., Ross, E., Sanchez Alvarado, A., Kempa, S., Dieterich, C., Rajewsky, N. and Chen, W. (2011) ‘De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics’, Genome Res 21(7): 1193-200.
  7. Lüscher A., Önal P., Schweingruber A. M., Mäser P. (2007) ‘Adenosine kinase of Trypanosoma brucei and its role in susceptibility to adenosine antimetabolites’ J. Antimicrobial Agents & Chemotherapy, 51(11):3895-901.